B??l?g???ll?, th? ?ff??t ???ur? ?n th? m?dbr??n r?g??n ??ll?d the v?ntr?l tegmental location (VTA). N?ur?n?l fibers within the VTA ??nn??t t? the nucleus ???umb?n?, an area ?f th? brain chargeable for r?w?rd?.This reinforces the drug-taking actions and lowers sensitivity on the drug. Folks then choose greater and more Regular doses to achieve the i